Respiratory illnesses can be a real nuisance, especially during the flu season. With the ongoing pandemic and increasing instances of respiratory syncytial virus (RSV), COVID-19, human metapneumovirus (HMPV), adenovirus, and parainfluenza, taking precautions to avoid catching or developing a respiratory illness is more crucial than ever. This article not only compiles a list of the top five traditional hot spots for respiratory illnesses at your office and home but also provides valuable tips on how to prevent them. Moreover, we explore advanced treatment options for severe respiratory conditions, including lung valve replacement for cases like severe emphysema, alongside preventive measures to help you stay safe and healthy. 1. Doorknobs, and appliance and drawer handles Doorknobs and drawer handles are some of the most touched surfaces in any home or office. Unfortunately, they can also be hot spots for respiratory illnesses, as they can easily spread germs from one person to another. To avoid getting sick, make sure to wash your hands regularly, and consider wiping down these surfaces with a disinfectant wipe every few hours. 2. Keyboards and electronics keypads Keyboards and electronics keypads can also harbor germs and bacteria. They are frequently touched and seldom cleaned, making them a perfect breeding ground for respiratory viruses.